FXYD6 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant FXYD6.
Immunogen
Recombinant protein corresponding to amino acids of human FXYD6.
Sequence
SRRCKCSFNQKPRAPGDEEAQVENLITANATEP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:10-1:20)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with FXYD6 polyclonal antibody (Cat # PAB24172) shows strong cytoplasmic positivity in cells in tubules. -
Gene Info — FXYD6
Entrez GeneID
53826Protein Accession#
Q9H0Q3Gene Name
FXYD6
Gene Alias
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Gene Description
FXYD domain containing ion transport regulator 6
Omim ID
606683Gene Ontology
HyperlinkGene Summary
This reference sequence was derived from multiple replicate ESTs and validated by human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD6, is novel and has not been characterized as a protein. Multiple alternatively spliced transcript variants that encode the same protein isoform have been described. RefSeq curation by Kathleen J. Sweadner, Ph.D., sweadner@helix.mgh.harvard.edu.
Other Designations
FXYD domain-containing ion transport regulator 6|phosphohippolin
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Interactome
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Disease
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