AFF3 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human tonsil with AFF3 polyclonal antibody (Cat # PAB24068) shows strong nuclear positivity in non-germinal center cells at 1:50-1:200 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant AFF3.
Immunogen
Recombinant protein corresponding to amino acids of human AFF3.
Sequence
QSHLVGVPKPGVPQTPVNKIDEHFVADSRAQNQPSSICSTTTSTPAAVPVQQSKRGTMGWQKAGHPPSDGQQRATQQGSLRTLLGDGVGRQQPRAKQVCNVEVGLQTQERPPAMAAKHSSSGHCVQNFPP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human tonsil with AFF3 polyclonal antibody (Cat # PAB24068) shows strong nuclear positivity in non-germinal center cells at 1:50-1:200 dilution. -
Gene Info — AFF3
Entrez GeneID
3899Protein Accession#
P51826Gene Name
AFF3
Gene Alias
LAF4, MLLT2-like
Gene Description
AF4/FMR2 family, member 3
Omim ID
601464Gene Ontology
HyperlinkGene Summary
This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq
Other Designations
MLLT2-related protein|lymphoid nuclear protein 4|lymphoid nuclear protein related to AF4
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Interactome
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Disease
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