Western blot analysis of PRMT8 polyclonal antibody (Cat # PAB2400) in K-562 cell line lysates (35 ug/lane). PRMT8 (arrow) was detected using the purified polyclonal antibody.
Western Blot (Transfected lysate)
Western blot analysis of PRMT8 (arrow) using rabbit PRMT8 polyclonal antibody (Cat # PAB2400). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PRMT8 gene (Lane 2) (Origene Technologies).
Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation (Lee et al., 2005 [PubMed 16051612]).[supplied by OMIM