KCNE1L polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebellum with KCNE1L polyclonal antibody (Cat # PAB23924) shows strong cytoplasmic positivity in purkinje cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant KCNE1L.
Immunogen
Recombinant protein corresponding to amino acids of human KCNE1L.
Sequence
MNCSESQRLRTLLSRLLLELHHRGNASGLGAGPRPSMGMGVVPDPFVGREVTSAKGDDA
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebellum with KCNE1L polyclonal antibody (Cat # PAB23924) shows strong cytoplasmic positivity in purkinje cells. -
Gene Info — KCNE1L
Entrez GeneID
23630Protein Accession#
Q9UJ90Gene Name
KCNE1L
Gene Alias
KCNE5
Gene Description
KCNE1-like
Omim ID
300328Gene Ontology
HyperlinkGene Summary
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a membrane protein which has sequence similarity to the KCNE1 gene product, a member of the potassium channel, voltage-gated, isk-related subfamily. This intronless gene is deleted in AMME contiguous gene syndrome and may be involved in the cardiac and neurologic abnormalities found in the AMME contiguous gene syndrome. [provided by RefSeq
Other Designations
AMMECR2 protein|OTTHUMP00000023845|cardiac voltage-gated potassium channel accessory subunit 5|potassium voltage-gated channel subfamily E member 1-like protein|potassium voltage-gated channel, Isk-related family, member 1-like|voltage-gated potassium cha
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Interactome
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Disease
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