RP1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with RP1 polyclonal antibody (Cat # PAB23915) shows moderate cytoplasmic positivity in subsets of tubules at 1:1000-1:2500 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant RP1.
Immunogen
Recombinant protein corresponding to amino acids of human RP1.
Sequence
VTCSPCEMCTVNKAYSPKETCNPSDTFFPSDGYGVDQTSMNKACFLGEVCSLTDTVFSDKACAQKENHTYEGACPIDETYVPVNVCNTIDFLNSKENTYTDNLDSTEELERGDDIQKDLNILTDPEYKNGFNTLVSHQNVSNLSSCG
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:1000-1:2500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with RP1 polyclonal antibody (Cat # PAB23915) shows moderate cytoplasmic positivity in subsets of tubules at 1:1000-1:2500 dilution. -
Gene Info — RP1
Entrez GeneID
6101Protein Accession#
P56715Gene Name
RP1
Gene Alias
DCDC4A, ORP1
Gene Description
retinitis pigmentosa 1 (autosomal dominant)
Gene Ontology
HyperlinkGene Summary
Initially named for its response to in vivo retinal oxygen levels (designated ORP1 for 'oxygen-regulated protein-1'), this gene was subsequently linked to autosomal dominant retinitis pigmentosa and was renamed RP1 for 'retinitis pigmentosa 1'. The data suggest that mutations in this gene cause dominant RP, and that the encoded protein has an important but unknown role in photoreceptor biology. There is evidence for at least one transcript variant that overlaps the current reference sequence and which has several exons upstream and downstream of the current reference sequence. However, the full-length nature of this variant cannot be determined at this time. [provided by RefSeq
Other Designations
oxygen-regulated protein 1|retinitis pigmentosa RP1 protein
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Interactome
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Disease
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