ETFDH polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ETFDH.
Immunogen
Recombinant protein corresponding to amino acids of human ETFDH.
Sequence
LAVAHEKDIRVCLVEKAAQIGAHTLSGACLDPGAFKELFPDWKEKGAPLNTPVTEDRFGILTEKYRIPVPILPGLPMN
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with ETFDH polyclonal antibody (Cat # PAB23884).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human stomach with ETFDH polyclonal antibody (Cat # PAB23884) shows strong cytoplasmic positivity in glandular cells. -
Gene Info — ETFDH
Entrez GeneID
2110Protein Accession#
Q16134Gene Name
ETFDH
Gene Alias
ETFQO, MADD
Gene Description
electron-transferring-flavoprotein dehydrogenase
Gene Ontology
HyperlinkGene Summary
Electron-transferring-flavoprotein dehydrogenase in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in the mitochondrial membrane. The protein is synthesized as a 67-kDa precursor which is targeted to mitochondria and processed in a single step to a 64-kDa mature form located in the mitochondrial membrane. Deficiency in electron-transferring-flavoprotein dehydrogenase have been demonstrated in some patients with type II glutaricacidemia. [provided by RefSeq
Other Designations
ETF-ubiquinone oxidoreductase|Electron transfer flavoprotein:ubiquinone oxidoreductase|electron transfer flavoprotein ubiquinone oxidoreductase
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Interactome
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Disease
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