CLC polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human bone marrow with CLC polyclonal antibody (Cat # PAB23850) shows strong cytoplasmic positivity in subsets of hematopoietic cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant CLC.
Immunogen
Recombinant protein corresponding to amino acids of human CLC.
Sequence
LACFLNEPYLQVDFHTEMKEESDIVFHFQVCFGRRVVMNSREYGAWKQQVESKNMPFQDGQEFELSISVLPDKYQVM
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:2500-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human bone marrow with CLC polyclonal antibody (Cat # PAB23850) shows strong cytoplasmic positivity in subsets of hematopoietic cells. -
Gene Info — CLC
Entrez GeneID
1178Protein Accession#
Q05315Gene Name
CLC
Gene Alias
LGALS10, LPPL_HUMAN, MGC149659
Gene Description
Charcot-Leyden crystal protein
Omim ID
153310Gene Ontology
HyperlinkGene Summary
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias. [provided by RefSeq
Other Designations
Charot-Leyden crystal protein|eosinophil lysophospholipase|galactin-10|galectin 10|lysolecithin acylhydrolase
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Interactome
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Disease
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