GFER polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant GFER.
Immunogen
Recombinant protein corresponding to amino acids of human GFER.
Sequence
QQDMAQFIHLFSKFYPCEECAEDLRKRLCRNHPDTRTRACFTQWLCHLHNEVNRKLGKPDFDCSKVDERWRDGWKDGSCD
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human liver with GFER polyclonal antibody (Cat # PAB23772) shows strong cytoplasmic positivity in hepatocytes at 1:50-1:200 dilution.Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with GFER polyclonal antibody (Cat # PAB23772) at 1-4 ug/mL dilution shows positivity in cytoplasm and mitochondria. -
Gene Info — GFER
Entrez GeneID
2671Protein Accession#
P55789Gene Name
GFER
Gene Alias
ALR, ERV1, HERV1, HPO, HPO1, HPO2, HSS
Gene Description
growth factor, augmenter of liver regeneration
Omim ID
600924Gene Ontology
HyperlinkGene Summary
The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene. [provided by RefSeq
Other Designations
ERV1 homolog|augmenter of liver regeneration|erv1-like growth factor|hepatic regenerative stimulation substance|hepatopoietin protein|truncated augmenter of liver regeneration
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