LEO1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human rectum with LEO1 polyclonal antibody (Cat # PAB23722) shows moderate nuclear and cytoplasmic positivity in glandular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant LEO1.
Immunogen
Recombinant protein corresponding to amino acids of human LEO1.
Sequence
DEERAQGSDEDKLQNSDDDEKMQNTGDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEGQPQLSDEEKMQNSDDER
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human rectum with LEO1 polyclonal antibody (Cat # PAB23722) shows moderate nuclear and cytoplasmic positivity in glandular cells. -
Gene Info — LEO1
Entrez GeneID
123169Protein Accession#
Q8WVC0Gene Name
LEO1
Gene Alias
RDL
Gene Description
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
Omim ID
610507Gene Ontology
HyperlinkGene Summary
LEO1, parafibromin (CDC73; MIM 607393), CTR9 (MIM 609366), and PAF1 (MIM 610506) form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al., 2005 [PubMed 15632063]).[supplied by OMIM
Other Designations
Leo1, Paf1/RNA polymerase II complex component, homolog|replicative senescence downregulated leo1-like|senescence downregulated leo1-like
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