ZMIZ2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ZMIZ2.
Immunogen
Recombinant protein corresponding to amino acids of human ZMIZ2.
Sequence
LMPSVMEMIAALGPGAAPFAPLQPPSVPAPSDYPGQGSSFLGPGTFPESFPPTTPSTPTLAEFTPGPPPISYQSDIPSSLLTSEKSTACLPSQMAPAGHLDPTHNPGTPGLHTSNL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human prostate with ZMIZ2 polyclonal antibody (Cat # PAB23684) shows moderate nuclear positivity in glandular cells.Immunofluorescence
Immunofluorescent staining of human cell line A-431 with ZMIZ2 polyclonal antibody (Cat # PAB23684) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli. -
Gene Info — ZMIZ2
Entrez GeneID
83637Protein Accession#
Q8NF64Gene Name
ZMIZ2
Gene Alias
DKFZp761I2123, KIAA1886, ZIMP7, hZIMP7
Gene Description
zinc finger, MIZ-type containing 2
Omim ID
611196Gene Ontology
HyperlinkGene Summary
ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM
Other Designations
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Interactome
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