IGFALS polyclonal antibody
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with IGFALS polyclonal antibody (Cat # PAB23681) at 1:250-1:500 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human testis with IGFALS polyclonal antibody (Cat # PAB23681) shows moderate cytoplasmic positivity in cells in seminiferus ducts at 1:50-1:200 dilution.
Immunofluorescence
Immunofluorescent staining of human cell line A-431 with IGFALS polyclonal antibody (Cat # PAB23681) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant IGFALS.
Immunogen
Recombinant protein corresponding to amino acids of human IGFALS.
Sequence
DCGCPLKALRDFALQNPSAVPRFVQAICEGDDCQPPAYTYNNITCASPPEVVGLDLRDLSEAHFAP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:250-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with IGFALS polyclonal antibody (Cat # PAB23681) at 1:250-1:500 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human testis with IGFALS polyclonal antibody (Cat # PAB23681) shows moderate cytoplasmic positivity in cells in seminiferus ducts at 1:50-1:200 dilution.Immunofluorescence
Immunofluorescent staining of human cell line A-431 with IGFALS polyclonal antibody (Cat # PAB23681) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli. -
Gene Info — IGFALS
Entrez GeneID
3483Protein Accession#
P35858Gene Name
IGFALS
Gene Alias
ALS
Gene Description
insulin-like growth factor binding protein, acid labile subunit
Omim ID
601489Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
Other Designations
INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN COMPLEX ACID LABILE CHAIN
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Interactome
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Disease
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