Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate). Lane 2: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells with MNS1 polyclonal antibody (Cat # PAB23653).
Immunohistochemical staining of human testis with MNS1 polyclonal antibody (Cat # PAB23653) shows strong cytoplasmic positivity in cells in seminiferus ducts while Leydig cells displayed strong cytoplasmic and nuclear staining.
This gene encodes a protein highly similar to the mouse meiosis-specific nuclear structural 1 protein. The mouse protein was shown to be expressed at the pachytene stage during spermatogenesis and may function as a nuclear skeletal protein to regulate nuclear morphology during meiosis. [provided by RefSeq