TOX3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant TOX3.
Immunogen
Recombinant protein corresponding to amino acids of human TOX3.
Sequence
SQGSEFTPQFPPQSLDLPSITISRNLVEQDGVLHSSGLHMDQSHTQVSQYRQDPSLIMRSIVHMTDAARSGVMP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human liver with TOX3 polyclonal antibody (Cat # PAB23652) shows moderate cytoplasmic and nuclear positivity in hepatocytes at 1:200-1:500 dilution. -
Gene Info — TOX3
Entrez GeneID
27324Protein Accession#
O15405Gene Name
TOX3
Gene Alias
CAGF9, TNRC9
Gene Description
TOX high mobility group box family member 3
Omim ID
611416Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two transcript variants encoding different isoforms have been found for this gene
Other Designations
trinucleotide repeat containing 9
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Interactome
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Disease
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