NLRP14 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant NLRP14.
Immunogen
Recombinant protein corresponding to amino acids of human NLRP14.
Sequence
EKAWSVSLKIFGKMNLKDLCERAKEEINWSAQTIGPDDAKAGETQEDQEAVLGDGTEYRNRIKEKFCITWDKKSLAGKPEDFHHGIAEKDRKLLEHLFDVDVK
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human stomach with NLRP14 polyclonal antibody (Cat # PAB23547) shows moderate cytoplasmic positivity in glandular cells. -
Gene Info — NLRP14
Entrez GeneID
338323Protein Accession#
Q86W24Gene Name
NLRP14
Gene Alias
CLR11.2, GC-LRR, NALP14, NOD5, PAN8
Gene Description
NLR family, pyrin domain containing 14
Omim ID
609665Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq
Other Designations
NACHT, LRR and PYD containing protein 14|NACHT, leucine rich repeat and PYD containing 14|nucleotide-binding oligomerization domain protein 5|nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 14
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Disease
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