AP3B2 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebellum with AP3B2 polyclonal antibody (Cat # PAB23545) shows moderate cytoplasmic positivity in Purkinje cells at 1:200-1:500 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant AP3B2.
Immunogen
Recombinant protein corresponding to amino acids of human AP3B2.
Sequence
APVFMSENEFKKEQGKLMGMNEITEKLMLPDTCRSDHIVVQKVTATANLGRVPCGTSDEYRFAGRTLTGGSLVLLTLDARPAGAAQLTVNSEKMVIGTMLVKDVIQ
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebellum with AP3B2 polyclonal antibody (Cat # PAB23545) shows moderate cytoplasmic positivity in Purkinje cells at 1:200-1:500 dilution. -
Gene Info — AP3B2
Entrez GeneID
8120Protein Accession#
Q13367Gene Name
AP3B2
Gene Alias
DKFZp686D17136, NAPTB
Gene Description
adaptor-related protein complex 3, beta 2 subunit
Omim ID
602166Gene Ontology
HyperlinkGene Summary
Adaptor protein-3 (AP3) is a heterotetrameric vesicle-coat protein complex. Some AP3 subunits are ubiquitously expressed, whereas others are expressed exclusively in neurons. The neuron-specific AP3 complex, which includes AP3B2, is thought to serve neuron-specific functions such as neurotransmitter release (Grabner et al., 2006 [PubMed 16788073]).[supplied by OMIM
Other Designations
Neuronal adaptin-like protein, beta-subunit
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Interactome
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Pathway
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Disease
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