RPGRIP1L polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant RPGRIP1L.
Immunogen
Recombinant protein corresponding to amino acids of human RPGRIP1L.
Sequence
KNTITLEVHQAYSTEYETIAACQLKFHEILEKSGRIFCTASLIGTKGDIPNFGTVEYWFRLRVPMDQAIRLYRERAKALGYITSNFKGPEHMQSLSQQAPKTAQLSSTDSTDGNL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human bronchus with RPGRIP1L polyclonal antibody (Cat # PAB23540) shows strong cytoplasmic positivity in respiratory epithelial cells at 1:50-1:200 dilution. -
Gene Info — RPGRIP1L
Entrez GeneID
23322Protein Accession#
Q68CZ1Gene Name
RPGRIP1L
Gene Alias
CORS3, DKFZp686C0668, JBTS7, KIAA1005, MKS5, NPHP8
Gene Description
RPGRIP1-like
Omim ID
610937Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene can localize to the basal body-centrosome complex or to primary cilia and centrosomes in ciliated cells. The encoded protein has been found to interact with nephrocystin-4. Defects in this gene are a cause of Joubert syndrome type 7 (JBTS7) and Meckel syndrome type 5 (MKS5). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
RPGR-interacting protein 1-like protein|protein fantom
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Interactome
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Disease
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