INSC polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant INSC.
Immunogen
Recombinant protein corresponding to amino acids of human INSC.
Sequence
CLQVENEHVLKSMKACVSETLSMLGQHFGQLLELALTREVQALVRKIDASDNIYTTESTTGNLFSLTQEGAPLCRIIAKEGGVVALFKVCRQDSFRCLY
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human colon with INSC polyclonal antibody (Cat # PAB23449) shows strong cytoplasmic and membranous positivity in glandular cells at 1:50-1:200 dilution. -
Gene Info — INSC
Entrez GeneID
387755Protein Accession#
Q1MX18Gene Name
INSC
Gene Alias
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Gene Description
inscuteable homolog (Drosophila)
Omim ID
610668Gene Ontology
HyperlinkGene Summary
In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 [PubMed 16458856]).[supplied by OMIM
Other Designations
inscuteable
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Interactome
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Disease
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