HVCN1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant HVCN1.
Immunogen
Recombinant protein corresponding to amino acids of human HVCN1.
Sequence
GIIISVKTRSERQLLRLKQMNVQLAAKIQHLEFSCSEKEQEIERLNKLLRQHGLLGEVN
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human tonsil with HVCN1 polyclonal antibody (Cat # PAB23414) shows strong cytoplasmic positivity in subsets of lymphoid cells outside reaction centra at 1:20-1:50 dilution. -
Gene Info — HVCN1
Entrez GeneID
84329Protein Accession#
Q96D96Gene Name
HVCN1
Gene Alias
HV1, MGC15619, VSOP
Gene Description
hydrogen voltage-gated channel 1
Omim ID
611227Gene Ontology
HyperlinkGene Summary
HVCN1 is a voltage-gated proton channel highly expressed in immune tissues. Channels like HVCN1 mediate the proton conductances required by phagocytic leukocytes for the oxidative burst that underlies microbial killing (Ramsey et al., 2006 [PubMed 16554753]).[supplied by OMIM
Other Designations
voltage sensor domain-only protein
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