HDAC10 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HDAC10 polyclonal antibody (Cat # PAB2340) in A-375 cell line lysates. HDAC10 (arrow) was detected using the purified polyclonal antibody.
Western Blot (Transfected lysate)
Western blot analysis of HDAC10 (arrow) using rabbit HDAC10 polyclonal antibody (Cat # PAB2340). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the HDAC10 gene (Lane 2) (Origene Technologies).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of HDAC10.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to amino acids 1-100 of human HDAC10.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HDAC10 polyclonal antibody (Cat # PAB2340) in A-375 cell line lysates. HDAC10 (arrow) was detected using the purified polyclonal antibody.Western Blot (Transfected lysate)
Western blot analysis of HDAC10 (arrow) using rabbit HDAC10 polyclonal antibody (Cat # PAB2340). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the HDAC10 gene (Lane 2) (Origene Technologies). -
Gene Info — HDAC10
Entrez GeneID
83933Protein Accession#
Q969S8Gene Name
HDAC10
Gene Alias
DKFZp761B039, MGC149722
Gene Description
histone deacetylase 10
Omim ID
608544Gene Ontology
HyperlinkGene Summary
Acetylation of histone core particles modulates chromatin structure and gene expression. The opposing enzymatic activities of histone acetyltransferases and histone deacetylases, such as HDAC10, determine the acetylation status of histone tails (Kao et al., 2002 [PubMed 11677242]).[supplied by OMIM
Other Designations
OTTHUMP00000028555
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Interactome
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Disease
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Publication Reference
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A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression.
Keedy KS, Archin NM, Gates AT, Espeseth A, Hazuda DJ, Margolis DM.
Journal of Virology 2009 Mar; 83(10):4749.
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Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.
Bradbury CA, Khanim FL, Hayden R, Bunce CM, White DA, Drayson MT, Craddock C, Turner BM.
Leukemia 2005 Oct; 19(10):1751.
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Chromosomal organization and localization of the novel class IV human histone deacetylase 11 gene.
Voelter-Mahlknecht S, Ho AD, Mahlknecht U.
International Journal of Molecular Medicine 2005 Oct; 16(4):589.
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A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression.
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