Western blot analysis of HDAC10 polyclonal antibody (Cat # PAB2340) in A-375 cell line lysates. HDAC10 (arrow) was detected using the purified polyclonal antibody.
Western Blot (Transfected lysate)
Western blot analysis of HDAC10 (arrow) using rabbit HDAC10 polyclonal antibody (Cat # PAB2340). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the HDAC10 gene (Lane 2) (Origene Technologies).
Acetylation of histone core particles modulates chromatin structure and gene expression. The opposing enzymatic activities of histone acetyltransferases and histone deacetylases, such as HDAC10, determine the acetylation status of histone tails (Kao et al., 2002 [PubMed 11677242]).[supplied by OMIM