BRWD2 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human testis with BRWD2 polyclonal antibody (Cat # PAB23377) shows strong cytoplasmic positivity in cells in seminiferous ducts.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant BRWD2.
Immunogen
Recombinant protein corresponding to amino acids of human BRWD2.
Sequence
ILILDLEVNQTVGVIAIERTGVPFLQVIPCFQRDGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCD
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human testis with BRWD2 polyclonal antibody (Cat # PAB23377) shows strong cytoplasmic positivity in cells in seminiferous ducts. -
Gene Info — BRWD2
Entrez GeneID
55717Protein Accession#
Q9BZH6Gene Name
BRWD2
Gene Alias
DKFZp434L1715, DR11, FLJ42531, WDR11, WDR15
Gene Description
bromodomain and WD repeat domain containing 2
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus. [provided by RefSeq
Other Designations
OTTHUMP00000020620|WD repeat domain 11|WD repeat domain 15|WD40 repeat domain 11 protein
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Interactome
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Disease
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