ANO6 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ANO6.
Immunogen
Recombinant protein corresponding to amino acids of human ANO6.
Sequence
EEDDDDGDIVLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLD
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with ANO6 polyclonal antibody (Cat # PAB23371) shows strong cytoplasmic and membranous positivity in exocrine glandular cells at 1:500-1:1000 dilution. -
Gene Info — ANO6
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Interactome
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Disease
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Publication Reference
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TMEM16F mediated phosphatidylserine exposure and microparticle release on erythrocyte contribute to hypercoagulable state in hyperuricemia.
Meishan Yan, Minghui Xu, Zhanni Li, Yao An, Zelong Wang, Shuli Li, Yingli Chen, Yanshi Xia, Liqiu Wang, Longlong Wang, Shuting Ji, Weijun Dong, Jialan Shi, Chunyan Gao.
Blood Cells, Molecules & Diseases 2022 May; 96:102666.
Application:Flow Cyt, Human, Red blood cells (RBCs).
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Hyperuricemia enhances procoagulant activity of vascular endothelial cells through TMEM16F regulated phosphatidylserine exposure and microparticle release.
Hongyin Yu, Zelong Wang, Zhanni Li, Yao An, Meishan Yan, Shuting Ji, Minghui Xu, Liqiu Wang, Weijun Dong, Jialan Shi, Chunyan Gao.
FASEB Journal 2021 Sep; 35(9):e21808.
Application:IF, WB-Tr, Human, HUVECs.
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TMEM16F mediated phosphatidylserine exposure and microparticle release on erythrocyte contribute to hypercoagulable state in hyperuricemia.
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