BFSP2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant BFSP2.
Immunogen
Recombinant protein corresponding to amino acids of human BFSP2.
Sequence
LSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEAGALLQAKQQAEVAHMSQTQEEKLAAALRVE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human lateral ventricle with BFSP2 polyclonal antibody (Cat # PAB23290) shows weak cytoplasmic positivity in neuronal cells.Immunofluorescence
Immunofluorescent staining of human cell line A-431 with BFSP2 polyclonal antibody (Cat # PAB23290) at 1-4 ug/mL dilution shows positivity in plasma membrane and cytoplasm. -
Gene Info — BFSP2
Entrez GeneID
8419Protein Accession#
Q13515Gene Name
BFSP2
Gene Alias
CP47, CP49, LIFL-L, MGC142078, MGC142080, PHAKOSIN
Gene Description
beaded filament structural protein 2, phakinin
Gene Ontology
HyperlinkGene Summary
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex. [provided by RefSeq
Other Designations
beaded filament protein CP49|bfps2, Cytoskeletal protein, 49-kD|phakinin
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