HISPPD1 polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against recombinant HISPPD1.
Immunogen
Recombinant protein corresponding to amino acids of human HISPPD1.
Sequence
LSVSSPEGTGTWLHYTSGVGTGRRRRRSGEQITSSPVSPKSLAFTSSIFGSWQQVVSENANYLRTPRTLVEQKQNPTVGSHCA
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with HISPPD1 polyclonal antibody (Cat # PAB23287) shows strong cytoplasmic positivity in cells in tubules while strong nuclear positivity in cells in glomeruli at 1:200-1:500 dilution. -
Gene Info — HISPPD1
Entrez GeneID
23262Protein Accession#
O43314Gene Name
HISPPD1
Gene Alias
FLJ21506, FLJ23463, IP7K2, KIAA0433, PPIP5K2, VIP2
Gene Description
histidine acid phosphatase domain containing 1
Omim ID
611648Gene Ontology
HyperlinkGene Summary
Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell signaling molecules. HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24) activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively (Fridy et al., 2007 [PubMed 17690096]).[supplied by OMIM
Other Designations
Histidine acid phosphatase domain containing 1|inositol heptaphosphate kinase 2
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