XPO6 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with XPO6 polyclonal antibody (Cat # PAB23249) shows strong cytoplasmic positivity in cells of tubules.
Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with XPO6 polyclonal antibody (Cat # PAB23249) at 1-4 ug/mL dilution shows positivity in nucleus, nucleoli and plasma membrane.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant XPO6.
Immunogen
Recombinant protein corresponding to amino acids of human XPO6.
Sequence
RPSPDVKAELFELLFRTLHHNWRYFFKSTVLASVQRGIAEEQMENEPQFSAIMQAFGQSFLQPDIHLFKQNLFYLETLNTKQKLYHKK
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:500-1:1000)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with XPO6 polyclonal antibody (Cat # PAB23249) shows strong cytoplasmic positivity in cells of tubules.Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with XPO6 polyclonal antibody (Cat # PAB23249) at 1-4 ug/mL dilution shows positivity in nucleus, nucleoli and plasma membrane. -
Gene Info — XPO6
Entrez GeneID
23214Protein Accession#
Q96QU8Gene Name
XPO6
Gene Alias
EXP6, FLJ22519, KIAA0370, RANBP20
Gene Description
exportin 6
Omim ID
608411Gene Ontology
HyperlinkGene Summary
Exportins, such as XPO6, recruit cargo in the nucleoplasm in the presence of RAN (MIM 601179)-GTP and form ternary export complexes. These complexes are transported through nuclear pore complexes to the cytoplasm, where GTP is hydrolyzed and the export complex is disassembled.[supplied by OMIM
Other Designations
RAN binding protein 20
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Interactome
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Disease
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