PDSS1 polyclonal antibody
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with PDSS1 polyclonal antibody (Cat # PAB23207).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human liver with PDSS1 polyclonal antibody (Cat # PAB23207) shows strong cytoplasmic and nuclear positivity in hepatocytes.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant PDSS1.
Immunogen
Recombinant protein corresponding to amino acids of human PDSS1.
Sequence
MGKPTSADLKLGLATGPVLFACQQFPEMNAMIMRRFSLPGDVDRARQYVLQSDGVQQTTYLAQQYCHEAIREISKLRPSPERDALIQLSEIVLT
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with PDSS1 polyclonal antibody (Cat # PAB23207).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human liver with PDSS1 polyclonal antibody (Cat # PAB23207) shows strong cytoplasmic and nuclear positivity in hepatocytes. -
Gene Info — PDSS1
Entrez GeneID
23590Protein Accession#
Q5T2R2Gene Name
PDSS1
Gene Alias
COQ1, DPS, MGC70953, RP13-16H11.3, SPS, TPRT, TPT, hDPS1
Gene Description
prenyl (decaprenyl) diphosphate synthase, subunit 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in this gene are a cause of coenzyme Q10 deficiency. [provided by RefSeq
Other Designations
OTTHUMP00000019346|coenzyme Q1 homolog|polyprenyl pyrophosphate synthetase|prenyl diphosphate synthase, subunit 1|subunit 1 of decaprenyl diphosphate synthase|trans-prenyltransferase (TPT)
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Interactome
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Pathway
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Disease
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