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Last updated: 2016/9/25
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DCLRE1A polyclonal antibody

  • Catalog # : PAB23083
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against recombinant DCLRE1A.
  • Immunogen:
  • Recombinant protein corresponding to amino acids of human DCLRE1A.
  • Sequence:
  • TTPGKLCRTQKSQHVSPKIRPVYDGYCPNCQMPFSSLIGQTPRWHVFECLDSPPRSETECPDGLLCTSTIPFHYKRYTHFLLAQSRAG
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (1:20-1:50)
    Immunofluorescence (1-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of human placenta with DCLRE1A polyclonal antibody (Cat # PAB23083) shows strong nuclear positivity in trophoblastic cells.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of human cell line A-431 with DCLRE1A polyclonal antibody (Cat # PAB23083) at 1-4 ug/mL dilution shows positivity in nucleus and nucleoli.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 9937
  • Gene Name:
  • DCLRE1A
  • Gene Alias:
  • KIAA0086,PSO2,SNM1,SNM1A,hSNM1
  • Gene Description:
  • DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae)
  • Gene Summary:
  • DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1A is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]).[supplied by OMIM
  • Other Designations:
  • DNA-crosslink repair gene SNM1,OTTHUMP00000020516,OTTHUMP00000020517
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