DCLRE1A polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human placenta with DCLRE1A polyclonal antibody (Cat # PAB23083) shows strong nuclear positivity in trophoblastic cells.
Immunofluorescence
Immunofluorescent staining of human cell line A-431 with DCLRE1A polyclonal antibody (Cat # PAB23083) at 1-4 ug/mL dilution shows positivity in nucleus and nucleoli.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant DCLRE1A.
Immunogen
Recombinant protein corresponding to amino acids of human DCLRE1A.
Sequence
TTPGKLCRTQKSQHVSPKIRPVYDGYCPNCQMPFSSLIGQTPRWHVFECLDSPPRSETECPDGLLCTSTIPFHYKRYTHFLLAQSRAG
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human placenta with DCLRE1A polyclonal antibody (Cat # PAB23083) shows strong nuclear positivity in trophoblastic cells.Immunofluorescence
Immunofluorescent staining of human cell line A-431 with DCLRE1A polyclonal antibody (Cat # PAB23083) at 1-4 ug/mL dilution shows positivity in nucleus and nucleoli. -
Gene Info — DCLRE1A
Entrez GeneID
9937Protein Accession#
Q6PJP8Gene Name
DCLRE1A
Gene Alias
KIAA0086, PSO2, SNM1, SNM1A, hSNM1
Gene Description
DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae)
Omim ID
609682Gene Ontology
HyperlinkGene Summary
DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1A is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]).[supplied by OMIM
Other Designations
DNA-crosslink repair gene SNM1|OTTHUMP00000020516|OTTHUMP00000020517
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Interactome
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Disease
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