ARHGAP21 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human gallbladder with ARHGAP21 polyclonal antibody (Cat # PAB23039) shows distinct nuclear and cytoplasmic positivity in glandular cells at 1:200-1:500 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ARHGAP21.
Immunogen
Recombinant protein corresponding to amino acids of human ARHGAP21.
Sequence
VPPCLTTSAPLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHVSSLKGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEG
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human gallbladder with ARHGAP21 polyclonal antibody (Cat # PAB23039) shows distinct nuclear and cytoplasmic positivity in glandular cells at 1:200-1:500 dilution. -
Gene Info — ARHGAP21
Entrez GeneID
57584Protein Accession#
Q5T5U3Gene Name
ARHGAP21
Gene Alias
ARHGAP10, DKFZp761L0424, FLJ33323, FLJ90108
Gene Description
Rho GTPase activating protein 21
Omim ID
609870Gene Ontology
HyperlinkGene Summary
ARHGAP21 functions preferentially as a GTPase-activating protein (GAP) for CDC42 (MIM 116952) and regulates the ARP2/3 complex (MIM 604221) and F-actin dynamics at the Golgi through control of CDC42 activity (Dubois et al., 2005 [PubMed 15793564]).[supplied by OMIM
Other Designations
OTTHUMP00000019319|OTTHUMP00000045282|Rho-GTPase activating protein 10
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Interactome
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Disease
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