EXOC6 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant EXOC6.
Immunogen
Recombinant protein corresponding to amino acids of human EXOC6.
Sequence
TFSVSLQKQNKMKFGKNMYINRDRIPEERNETVLKHSLEEE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate).
Lane 2: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells with EXOC6 polyclonal antibody (Cat # PAB22976).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human adrenal gland with EXOC6 polyclonal antibody (Cat # PAB22976) shows strong membranous and cytoplasmic positivity in cortical cells. -
Gene Info — EXOC6
Entrez GeneID
54536Protein Accession#
Q8TAG9Gene Name
EXOC6
Gene Alias
DKFZp761I2124, EXOC6A, FLJ1125, FLJ11251, MGC33397, SEC15, SEC15L, SEC15L1, SEC15L3, Sec15p
Gene Description
exocyst complex component 6
Omim ID
609672Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the SEC15 family. It is highly similar to the protein encoded by Saccharomyces cerevisiae SEC15 gene. This protein is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast. It is one of the components of a multiprotein complex required for exocytosis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000020105|OTTHUMP00000059597|SEC15-like 1|SEC15-like protein 3|exocyst complex component Sec15A
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Interactome
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Disease
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