PLCH1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebral cortex with PLCH1 polyclonal antibody (Cat # PAB22962) shows moderate cytoplasmic positivity in neuronal cells.
Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with PLCH1 polyclonal antibody (Cat # PAB22962) at 1-4 ug/mL dilution shows positivity in endoplasmic reticulum.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant PLCH1.
Immunogen
Recombinant protein corresponding to amino acids of human PLCH1.
Sequence
SLTTCEYRREGTSQLASPLKLKYNQGVVEHFQRGLRNGYCKETLRPSVPEIFNNIQDVKTQSISYLAYQGAGFVHNHFSDSDAKMFQTCVPQQS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebral cortex with PLCH1 polyclonal antibody (Cat # PAB22962) shows moderate cytoplasmic positivity in neuronal cells.Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with PLCH1 polyclonal antibody (Cat # PAB22962) at 1-4 ug/mL dilution shows positivity in endoplasmic reticulum. -
Gene Info — PLCH1
Entrez GeneID
23007Protein Accession#
Q4KWH8Gene Name
PLCH1
Gene Alias
DKFZp434C1372, MGC117152, PLCL3, PLCeta1
Gene Description
phospholipase C, eta 1
Gene Ontology
HyperlinkGene Summary
PLCH1 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to generate second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) (Hwang et al., 2005 [PubMed 15702972]).[supplied by OMIM
Other Designations
phospholipase C-eta1a|phospholipase C-eta1b|phospholipase C-like 3
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Interactome
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Disease
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