AMTN polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant AMTN.
Immunogen
Recombinant protein corresponding to amino acids of human AMTN.
Sequence
SLPQLKPALGLPPTKLAPDQGTLPNQQQSNQVFPSLSLIPLTQMLTLGPDLHLLNPAAGMTPGTQTHPLTLGGLNVQQQLHPHVLPIFVTQLGAQ
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebellum with AMTN polyclonal antibody (Cat # PAB22952) shows moderate cytoplasmic positivity in purkinje cells at 1:50-1:200 dilution. -
Gene Info — AMTN
Entrez GeneID
401138Protein Accession#
Q6UX39Gene Name
AMTN
Gene Alias
MGC148132, MGC148133, UNQ689
Gene Description
amelotin
Omim ID
610912Gene Ontology
HyperlinkGene Summary
The mineralized portions of teeth, the dentin and enamel, are formed by mesenchyme-derived odontoblasts and epithelium-derived ameloblasts, respectively. As ameloblasts differentiate, they deposit specific proteins necessary for enamel formation, including amelogenin (AMELX; MIM 300391), enamelin (ENAM; MIM 606585), and ameloblastin (AMBN; MIM 601259), in the organic enamel matrix. Amelotin is specifically expressed in maturation-stage ameloblasts (Iwasaki et al., 2005 [PubMed 16304441]).[supplied by OMIM
Other Designations
RSTI689
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