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Last updated: 2017/3/26
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MAP3K10 polyclonal antibody

  • Catalog # : PAB2293
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of MAP3K10.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human MAP3K10.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • Western Blot (1:1000)
    Immunohistochemistry (1:50-100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • The MAP3K10 polyclonal antibody (Cat # PAB2293) is used in Western blot to detect MAP3K10 in transfected COS-7 cell lysate. Data is kindly provided by Drs. M.K. Barthwal and A. Rana from Texas A&M University, Health Science Center (Temple, TX) .
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human cancer tissue reacted with the MAP3K10 polyclonal antibody (Cat # PAB2293) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 4294
  • Gene Name:
  • MAP3K10
  • Gene Alias:
  • MLK2,MST
  • Gene Description:
  • mitogen-activated protein kinase kinase kinase 10
  • Gene Summary:
  • The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq
  • Other Designations:
  • MKN28 derived nonreceptor_type serine/threonine kinase,MKN28 kinase,mixed lineage kinase 2
  • Gene Pathway
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