ARAP2 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ARAP2.
Immunogen
Recombinant protein corresponding to amino acids of human ARAP2.
Sequence
HCLEHKDDKLRNRPRKHRSFNCLEDTEPEAPLGQPKGHKGLKTLRKTEDRNSKATLDSDHKLPSRVIEELNVVLQRSRTLPKELQDEQI
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:500-1:1000)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with ARAP2 polyclonal antibody (Cat # PAB22927) at 1:250-1:500 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human bone marrow with ARAP2 polyclonal antibody (Cat # PAB22927) shows strong cytoplasmic positivity in bone marrow poietic cells at 1:500-1:1000 dilution. -
Gene Info — ARAP2
Entrez GeneID
116984Protein Accession#
Q8WZ64Gene Name
ARAP2
Gene Alias
CENTD1, FLJ13675, FLJ44916, KIAA0580, PARX
Gene Description
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Omim ID
606645Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq
Other Designations
Arf and Rho GAP adapter protein 2|centaurin, delta 1
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Interactome
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Pathway
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