GCC2 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human duodenum with GCC2 polyclonal antibody (Cat # PAB22917) shows moderate cytoplasmic and membranous positivity in glandular cells at 1:200-1:500 dilution.
Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with GCC2 polyclonal antibody (Cat # PAB22917) at 1-4 ug/mL dilution shows positivity in nucleus, cytoplasm and golgi apparatus.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant GCC2.
Immunogen
Recombinant protein corresponding to amino acids of human GCC2.
Sequence
QNISEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQDNQICSIL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human duodenum with GCC2 polyclonal antibody (Cat # PAB22917) shows moderate cytoplasmic and membranous positivity in glandular cells at 1:200-1:500 dilution.Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with GCC2 polyclonal antibody (Cat # PAB22917) at 1-4 ug/mL dilution shows positivity in nucleus, cytoplasm and golgi apparatus. -
Gene Info — GCC2
Entrez GeneID
9648Protein Accession#
Q8IWJ2Gene Name
GCC2
Gene Alias
GCC185, KIAA0336
Gene Description
GRIP and coiled-coil domain containing 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a peripheral membrane protein localized to the trans-Golgi network. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
CLL-associated antigen KW-11|CTCL tumor antigen se1-1|GRIP and coiled-coil domain-containing 2|GRIP coiled-coil protein GCC185
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