CLNK polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human testis with CLNK polyclonal antibody (Cat # PAB22893) shows strong cytoplasmic positivity in spermatogonia.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant CLNK.
Immunogen
Recombinant protein corresponding to amino acids of human CLNK.
Sequence
QGNRKTTKEGSNDLKFQNFSLPKNRSWPRINSATGQYQRMNKPLLDWERNFAAVLDGAKGHSDDDYDDPELR
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human testis with CLNK polyclonal antibody (Cat # PAB22893) shows strong cytoplasmic positivity in spermatogonia. -
Gene Info — CLNK
Entrez GeneID
116449Protein Accession#
Q7Z7G1Gene Name
CLNK
Gene Alias
MGC35197, MIST
Gene Description
cytokine-dependent hematopoietic cell linker
Omim ID
611434Gene Ontology
HyperlinkGene Summary
MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1; MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 [PubMed 10562326]; Goitsuka et al., 2000, 2001 [PubMed 10744659] [PubMed 11463797]).[supplied by OMIM
Other Designations
mast cell immunoreceptor signal transducer
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Interactome
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Disease
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