CERKL polyclonal antibody
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with CERKL polyclonal antibody (Cat # PAB22874).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with CERKL polyclonal antibody (Cat # PAB22874) shows strong cytoplasmic positivity in exocrine glandular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant CERKL.
Immunogen
Recombinant protein corresponding to amino acids of human CERKL.
Sequence
IARNTSRPEFIKHLKRYASVKNQFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRLHPRLISLYGGSMEEMI
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with CERKL polyclonal antibody (Cat # PAB22874).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with CERKL polyclonal antibody (Cat # PAB22874) shows strong cytoplasmic positivity in exocrine glandular cells. -
Gene Info — CERKL
Entrez GeneID
375298Protein Accession#
Q49MI3Gene Name
CERKL
Gene Alias
RP26
Gene Description
ceramide kinase-like
Gene Ontology
HyperlinkGene Summary
Ceramide kinases convert the sphingolipid metabolite ceramide into ceramide-1-phosphate, both key mediators of cellular apoptosis and survival. Ceramide metabolism plays an essential role in the viability of neuronal cells, the membranes of which are particularly rich in sphingolipids (Tuson et al., 2004 [PubMed 14681825]).[supplied by OMIM
Other Designations
ceramide kinase-like protein|retinitis pigmentosa 26 (autosomal recessive)
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Disease
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