AGXT polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant AGXT.
Immunogen
Recombinant protein corresponding to amino acids of human AGXT.
Sequence
HPMTKDPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYKCLLLVDSVASLGGTPLYMDRQGIDILYSGS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:1000-1:2500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human liver with AGXT polyclonal antibody (Cat # PAB22869) shows strong cytoplasmic positivity in granular pattern in hepatocytes at 1:1000-1:2500 dilution. -
Gene Info — AGXT
Entrez GeneID
189Protein Accession#
P21549Gene Name
AGXT
Gene Alias
AGT, AGT1, AGXT1, PH1, SPAT, SPT, TLH6
Gene Description
alanine-glyoxylate aminotransferase
Gene Ontology
HyperlinkGene Summary
This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. [provided by RefSeq
Other Designations
L-alanine: glyoxylate aminotransferase 1|hepatic peroxisomal alanine:glyoxylate aminotransferase|serine-pyruvate aminotransferase|serine:pyruvate aminotransferase
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