PEAR1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant PEAR1.
Immunogen
Recombinant protein corresponding to amino acids of human PEAR1.
Sequence
PSDPNTCSFWESFTTTTKESHSRPFSLLPSEPCERPWEGPHTCPQPTVVYRTVYRQVVKTDHRQRLQCCHGFYES
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human bone marrow with PEAR1 polyclonal antibody (Cat # PAB22861) shows strong positivity in megakaryocytes and platelets. -
Gene Info — PEAR1
Entrez GeneID
375033Protein Accession#
Q5VY43Gene Name
PEAR1
Gene Alias
FLJ00193, JEDI, MEGF12
Gene Description
platelet endothelial aggregation receptor 1
Omim ID
610278Gene Ontology
HyperlinkGene Summary
PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (Nanda et al., 2005 [PubMed 15851471]).[supplied by OMIM
Other Designations
OTTHUMP00000038718|multiple EGF-like-domains 12
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Disease
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