TNMD polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant TNMD.
Immunogen
Recombinant protein corresponding to amino acids of human TNMD.
Sequence
GIEFDPMLDERGYCCIYCRRGNRYCRRVCEPLLGYYPYPYCYQGGRVICRV
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebellum with TNMD polyclonal antibody (Cat # PAB22840) shows strong nuclear positivity in purkinje cells at 1:50-1:200 dilution. -
Gene Info — TNMD
Entrez GeneID
64102Protein Accession#
Q9H2S6Gene Name
TNMD
Gene Alias
BRICD4, CHM1-LIKE, CHM1L, TEM
Gene Description
tenomodulin
Omim ID
300459Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated. [provided by RefSeq
Other Designations
BRICHOS domain containing 4|OTTHUMP00000023651|chondromodulin I-like|myodulin|tendin|tenomodulin protein
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Interactome
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Disease
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