BSN polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant BSN.
Immunogen
Recombinant protein corresponding to amino acids of human BSN.
Sequence
AQEHTFLATATTVSITMASSVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRGRPREAKFARYNLPNQVAPLA
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human lateral ventricle with BSN polyclonal antibody (Cat # PAB22825) shows distinct positivity in neuropil. -
Gene Info — BSN
Entrez GeneID
8927Protein Accession#
Q9UPA5Gene Name
BSN
Gene Alias
ZNF231
Gene Description
bassoon (presynaptic cytomatrix protein)
Omim ID
604020Gene Ontology
HyperlinkGene Summary
Neurotransmitters are released from a specific site in the axon terminal called the active zone, which is composed of synaptic vesicles and a meshwork of cytoskeleton underlying the plasma membrane. The protein encoded by this gene is thought to be a scaffolding protein involved in organizing the presynaptic cytoskeleton. The gene is expressed primarily in neurons in the brain. A similar gene product in rodents is concentrated in the active zone of axon terminals and tightly associated with cytoskeletal structures, and is essential for regulating neurotransmitter release from a subset of synapses. [provided by RefSeq
Other Designations
bassoon protein|neuronal double zinc finger protein|zinc finger protein 231
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Interactome
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Disease
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