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Last updated: 2017/1/15
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MAP3K6 polyclonal antibody

  • Catalog # : PAB2281
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of MAP3K6.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human MAP3K6.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • Western Blot (1:1000)
    Immunohistochemistry (1:50-100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • The MAP3K6 polyclonal antibody (Cat # PAB2281) is used in Western blot to detect MAP3K6 in NIH/3T3 cell lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with the MAP3K6 polyclonal antibody (Cat # PAB2281) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 9064
  • Gene Name:
  • MAP3K6
  • Gene Alias:
  • ASK2,MAPKKK6,MGC125653,MGC20114
  • Gene Description:
  • mitogen-activated protein kinase kinase kinase 6
  • Gene Summary:
  • This gene encodes a member of the serine/threonine protein kinase family. The encoded kinase was identified by its interaction with MAP3K5/ASK, a protein kinase and an activator of c-Jun kinase (MAPK7/JNK) and MAPK14/p38 kinase. This kinase was found to weakly activate MAPK7, but not MAPK1/ERK or MAPK14. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000005063,apoptosis signal-regulating kinase 2
  • Gene Pathway
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