NALCN polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant NALCN.
Immunogen
Recombinant protein corresponding to amino acids of human NALCN.
Sequence
QDNSMQPETSSQQQLLSPTLSDRGGSRQDAADAGKPQRKFGQWRLPSAPKPISHSVSSVNLRFGGRTTMKSVVCKMNPMTDAASCGSEVKKWWT
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:10-1:20)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebral cortex with NALCN polyclonal antibody (Cat # PAB22788) shows moderate cytoplasmic positivity in glial cells at 1:10-1:20 dilution. -
Gene Info — NALCN
Entrez GeneID
259232Protein Accession#
Q8IZF0Gene Name
NALCN
Gene Alias
CanIon, FLJ23913, FLJ44659, FLJ44764, MGC74524, VGCNL1, bA430M15.1
Gene Description
sodium leak channel, non-selective
Omim ID
611549Gene Ontology
HyperlinkGene Summary
NALCN forms a voltage-independent, nonselective, noninactivating cation channel permeable to Na+, K+, and Ca(2+). It is responsible for the neuronal background sodium leak conductance (Lu et al., 2007 [PubMed 17448995]).[supplied by OMIM
Other Designations
OTTHUMP00000018654|OTTHUMP00000018655|OTTHUMP00000018656|OTTHUMP00000040730|four repeat voltage-gated ion channel|voltage gated channel like 1
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Disease
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