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NALCN polyclonal antibody

  • Catalog # : PAB22787
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against recombinant NALCN.
  • Immunogen:
  • Recombinant protein corresponding to amino acids of human NALCN.
  • Sequence:
  • TYHCVVNDTKPGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNE
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (1:20-1:50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of human bone marrow with NALCN polyclonal antibody (Cat # PAB22787) shows strong cytoplasmic positivity in megakaryocytes at 1:20-1:50 dilution.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Gene Name:
  • NALCN
  • Gene Alias:
  • CanIon,FLJ23913,FLJ44659,FLJ44764,MGC74524,VGCNL1,bA430M15.1
  • Gene Description:
  • sodium leak channel, non-selective
  • Gene Summary:
  • NALCN forms a voltage-independent, nonselective, noninactivating cation channel permeable to Na+, K+, and Ca(2+). It is responsible for the neuronal background sodium leak conductance (Lu et al., 2007 [PubMed 17448995]).[supplied by OMIM
  • Other Designations:
  • OTTHUMP00000018654,OTTHUMP00000018655,OTTHUMP00000018656,OTTHUMP00000040730,four repeat voltage-gated ion channel,voltage gated channel like 1
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