MDFIC polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human duodenum with MDFIC polyclonal antibody (Cat # PAB22762) strong cytoplasmic positivity in glandular cells.
Immunofluorescence
Immunofluorescent staining of human cell line A-431 with MDFIC polyclonal antibody (Cat # PAB22762) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli and golgi apparatus.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant MDFIC.
Immunogen
Recombinant protein corresponding to amino acids of human MDFIC.
Sequence
QDQSIWGNPSDGELIRTQPQRLPQLQTSAQVPSGEEIGKIKNGHTGLSNGNGIHHGAKHGSADNRKLSAPVSQKMHRKIQSSLSVNSD
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human duodenum with MDFIC polyclonal antibody (Cat # PAB22762) strong cytoplasmic positivity in glandular cells.Immunofluorescence
Immunofluorescent staining of human cell line A-431 with MDFIC polyclonal antibody (Cat # PAB22762) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli and golgi apparatus. -
Gene Info — MDFIC
Entrez GeneID
29969Protein Accession#
Q9P1T7Gene Name
MDFIC
Gene Alias
HIC
Gene Description
MyoD family inhibitor domain containing
Gene Ontology
HyperlinkGene Summary
This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain. [provided by RefSeq
Other Designations
I-mfa domain-containing protein|MyoD family inhibitor domain containing protein
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Interactome
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Disease
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