LAGE3 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with LAGE3 polyclonal antibody (Cat # PAB22706) shows strong nuclear positivity in exocrine glandular cells at 1:50-1:200 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant LAGE3.
Immunogen
Recombinant protein corresponding to amino acids of human LAGE3.
Sequence
RDADADAGGGADGGDGRGGHSCRGGVDTAAAPAGGAPPAHAPGPGRDAAS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with LAGE3 polyclonal antibody (Cat # PAB22706) shows strong nuclear positivity in exocrine glandular cells at 1:50-1:200 dilution. -
Gene Info — LAGE3
Entrez GeneID
8270Protein Accession#
Q14657Gene Name
LAGE3
Gene Alias
CVG5, DXS9879E, DXS9951E, ESO3, ITBA2
Gene Description
L antigen family, member 3
Omim ID
300060Gene Ontology
HyperlinkGene Summary
This gene belongs to the ESO/LAGE gene family, members of which are clustered together on chromosome Xq28, and have similar exon-intron structures. Unlike the other family members which are normally expressed only in testis and activated in a wide range of human tumors, this gene is ubiquitously expressed in somatic tissues. The latter, combined with the finding that it is highly conserved in mouse and rat, suggests that the encoded protein is functionally important. An intronless pseudogene with high sequence similarity to this gene is located on chromosome 9. [provided by RefSeq
Other Designations
OTTHUMP00000032119|OTTHUMP00000061461
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