DPH3 polyclonal antibody

Catalog # PAB22674

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Size:100 uL
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining of human spleen with DPH3 polyclonal antibody (Cat # PAB22674) shows distinct cytoplasmic positivity in cells in red pulp.

Immunofluorescence
Application

Immunofluorescence

Immunofluorescent staining of human cell line U-2 OS with DPH3 polyclonal antibody (Cat # PAB22674) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli and cytoplasm.

  • Specifications

    Product Description

    Rabbit polyclonal antibody raised against recombinant DPH3.

    Immunogen

    Recombinant protein corresponding to amino acids of human DPH3.

    Sequence

    EDFQYDEDSETYFYPCPCGDNFSITKEDLENGEDVATCPSCSLIIKVIYDKDQFVCGETVPAPSANKELVK

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Purification

    Antigen affinity purification

    Isotype

    IgG

    Recommend Usage

    Immunohistochemistry (1:50-1:200)
    Immunofluorescence (1-4 ug/mL)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)

    Storage Instruction

    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining of human spleen with DPH3 polyclonal antibody (Cat # PAB22674) shows distinct cytoplasmic positivity in cells in red pulp.

    Immunofluorescence

    Immunofluorescent staining of human cell line U-2 OS with DPH3 polyclonal antibody (Cat # PAB22674) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli and cytoplasm.
  • Gene Info — DPH3

    Entrez GeneID

    285381

    Protein Accession#

    Q96FX2

    Gene Name

    DPH3

    Gene Alias

    DELGIP, DELGIP1, DESR1, DPH3A, KTI11, MGC20197, ZCSL2

    Gene Description

    DPH3, KTI11 homolog (S. cerevisiae)

    Omim ID

    608959

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a CSL zinc finger-containing protein that is required for dipthamide biosynthesis. The encoded protein is necessary for the initial step in the modification of a histidine residue in elongation factor-2 to diphthamide. This modified residue is a target for ADP ribosylation by the bacterial toxins diphtheria toxin and Pseudomonas exotoxin A. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq

    Other Designations

    DPH3 homolog (KTI11, S. cerevisiae)|DPH3A, KTI11 homolog A|deafness locus putative guanine nucleotide exchange factor interacting protein 1|zinc finger, CSL domain containing 2|zinc finger, CSL-type containing 2

Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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