SEMA3F polyclonal antibody

Catalog # PAB22649

Size

Price

Stock

Quantity

Size:100 uL
Price: USD $ 428.00
Stock:
order now, ship in 5 days
abnova-minus
abnova-plus

* The price is valid only in USA. Please select country.

Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining of human cerebellum with SEMA3F polyclonal antibody (Cat # PAB22649) shows strong cytoplasmic positivity in Purkinje cells.

  • Specifications

    Product Description

    Rabbit polyclonal antibody raised against recombinant SEMA3F.

    Immunogen

    Recombinant protein corresponding to amino acids of human SEMA3F.

    Sequence

    TPPYQELAQLLAQPEVGLIHQYCQGYWRHVPPSPREAPGAPRSPEPQDQKKPRNRRHHPPDT

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Purification

    Antigen affinity purification

    Isotype

    IgG

    Recommend Usage

    Immunohistochemistry (1:200-1:500)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)

    Storage Instruction

    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining of human cerebellum with SEMA3F polyclonal antibody (Cat # PAB22649) shows strong cytoplasmic positivity in Purkinje cells.
  • Gene Info — SEMA3F

    Entrez GeneID

    6405

    Protein Accession#

    Q13275

    Gene Name

    SEMA3F

    Gene Alias

    SEMA-IV, SEMA4, SEMAK

    Gene Description

    sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F

    Omim ID

    601124

    Gene Ontology

    Hyperlink

    Gene Summary

    The semaphorins are a family of proteins that are involved in signaling. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues (Kolodkin et al., 1993 [PubMed 8269517]). Sequence comparisons have grouped the secreted semaphorins into 3 general classes, all of which also have an immunoglobulin domain. The semaphorin III family, consisting of human semaphorin III (SEMA3A; MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E, all have a basic domain at the C terminus. Chicken collapsin contributes to path finding by axons during development by inhibiting extension of growth cones (Luo et al., 1993 [PubMed 8402908]) through an interaction with a collapsin response mediator protein of relative molecular mass 62K (CRMP62) (Goshima et al., 1995 [PubMed 7637782]), a putative homolog of an axonal guidance associated UNC33 gene product (MIM 601168). SEMA3F is a secreted member of the semaphorin III family.[supplied by OMIM

    Other Designations

    sema IV|sema domain, immunoglobulin domain (Ig), short basic domain, secreted, 3F|semaphorin 3F|semaphorin III/F|semaphorin IV

  • Interactomes
  • Pathways
  • Diseases
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
4 Products to Compare
Remove All