ZC3H12A polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ZC3H12A.
Immunogen
Recombinant protein corresponding to amino acids of human ZC3H12A.
Sequence
AFPPREYWSEPYPLPPPTSVLQEPPVQSPGAGRSPWGRAGSLAKEQASVYTKLCGVFPPHLVEAVMGRFPQLLDPQQLAAEILSYKSQHPS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with ZC3H12A polyclonal antibody (Cat # PAB22605) shows strong cytoplasmic positivity in cells in tubules at 1:200-1:500 dilution.Immunofluorescence
Immunofluorescent staining of human cell line U-251MG with ZC3H12A polyclonal antibody (Cat # PAB22605) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli and cytoplasm. -
Gene Info — ZC3H12A
Entrez GeneID
80149Protein Accession#
Q5D1E8Gene Name
ZC3H12A
Gene Alias
FLJ23231, MCPIP, MCPIP1, RP3-423B22.1, dJ423B22.1
Gene Description
zinc finger CCCH-type containing 12A
Omim ID
610562Gene Ontology
HyperlinkGene Summary
ZC3H12A is an MCP1 (CCL2; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.[supplied by OMIM
Other Designations
MCP induced protein 1|MCP-1 treatment-induced protein|MCP-induced protein 1|OTTHUMP00000004398|OTTHUMP00000004399
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