CACNA2D4 polyclonal antibody

Catalog # PAB22598

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Size:100 uL
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining of human heart muscle with CACNA2D4 polyclonal antibody (Cat # PAB22598) shows strong cytoplasmic positivity in myocytes.

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against recombinant CACNA2D4.

    Immunogen

    Recombinant protein corresponding to amino acids of human CACNA2D4.

    Sequence

    NDFINIIAYNDYVHYIEPCFKGILVQADRDNREHFKLLVEELMVKGVGVVDQALREAFQILKQFQEAKQGSLCNQAIM

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Purification

    Antigen affinity purification

    Isotype

    IgG

    Recommend Usage

    Immunohistochemistry (1:50-1:200)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)

    Storage Instruction

    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining of human heart muscle with CACNA2D4 polyclonal antibody (Cat # PAB22598) shows strong cytoplasmic positivity in myocytes.
  • Gene Info — CACNA2D4

    Entrez GeneID

    93589

    Protein Accession#

    Q7Z3S7

    Gene Name

    CACNA2D4

    Gene Alias

    RCD4

    Gene Description

    calcium channel, voltage-dependent, alpha 2/delta subunit 4

    Omim ID

    608171 610478

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq

    Other Designations

    voltage-gated calcium channel alpha(2)delta-4 subunit

  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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