WRNIP1 polyclonal antibody

Catalog # PAB22586

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Size:100 uL
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot
Application

Western Blot

Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with WRNIP1 polyclonal antibody (Cat # PAB22586) at 1:250-1:500 dilution.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining of human testis with WRNIP1 polyclonal antibody (Cat # PAB22586) shows strong nuclear positivity in cells of seminiferus ducts at 1:10-1:20 dilution.

Immunofluorescence
Application

Immunofluorescence

Immunofluorescent staining of human cell line U-251MG with WRNIP1 polyclonal antibody (Cat # PAB22586) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli and mitochondria.

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against recombinant WRNIP1.

    Immunogen

    Recombinant protein corresponding to amino acids of human WRNIP1.

    Sequence

    YQGCHFIGMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKARLRNHQGPLPPVPLHLRNAPTRLMKDLGYG

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Purification

    Antigen affinity purification

    Isotype

    IgG

    Recommend Usage

    Immunohistochemistry (1:10-1:20)
    Western Blot (1:250-1:500)
    Immunofluorescence (1-4 ug/mL)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)

    Storage Instruction

    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot

    Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with WRNIP1 polyclonal antibody (Cat # PAB22586) at 1:250-1:500 dilution.

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining of human testis with WRNIP1 polyclonal antibody (Cat # PAB22586) shows strong nuclear positivity in cells of seminiferus ducts at 1:10-1:20 dilution.

    Immunofluorescence

    Immunofluorescent staining of human cell line U-251MG with WRNIP1 polyclonal antibody (Cat # PAB22586) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli and mitochondria.
  • Gene Info — WRNIP1

    Entrez GeneID

    56897

    Protein Accession#

    Q96S55

    Gene Name

    WRNIP1

    Gene Alias

    FLJ22526, RP11-420G6.2, WHIP, bA420G6.2

    Gene Description

    Werner helicase interacting protein 1

    Omim ID

    608196

    Gene Ontology

    Hyperlink

    Gene Summary

    Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Two transcript variants encoding different isoforms have been isolated for this gene. [provided by RefSeq

    Other Designations

    OTTHUMP00000015944|OTTHUMP00000015945|Werner helicase interacting protein|putative helicase RUVBL

  • Interactome
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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