WFDC1 polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human duodenum with WFDC1 polyclonal antibody (Cat # PAB22551) shows strong granular positivity in glandular cells at 1:200-1:500 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant WFDC1.
Immunogen
Recombinant protein corresponding to amino acids of human WFDC1.
Sequence
LLCPSGYECHILSPGDVAEGIPNRGQCVKQRRQADGRILRHKLYKEYPEGDSKNVAEPGRGQQKHFQ
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human duodenum with WFDC1 polyclonal antibody (Cat # PAB22551) shows strong granular positivity in glandular cells at 1:200-1:500 dilution. -
Gene Info — WFDC1
Entrez GeneID
58189Protein Accession#
Q9HC57Gene Name
WFDC1
Gene Alias
PS20
Gene Description
WAP four-disulfide core domain 1
Omim ID
605322Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81% amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene. [provided by RefSeq
Other Designations
WAP four-disulfide core domain 1 homolog|prostate stromal protein ps20
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Interactome
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Disease
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